• QUALISTAT
  • (Simvastatin)

  • Terramedic Products

  • How does it work?
  • Simvastatin is used to reduce LDL-cholesterol, apolipoprotein B, and triglyceride and to increase HDL-cholesterol in the treatment of hyperlipidaemia, including hypercholesterolaemia and combined hyperlipidaemia. Statins can be effective as adjunct therapy in patients with homozygous familial hypercholesterolaemia who have some LDL receptors function. Simvastatin is also given prophylactically to hypercholestorelaemic patients with ischemic heart disease.
  • How is it taken?
  • Simvastatin is given by mouth in an initial dose of 5 to 10 mg in the evening; an initial dose of 20 mg may be used In patients with ischaemic heart disease. The dose may be adjusted at intervals of not less than 4 weeks up to maximum of 80 mg once daily in the evening. Patients with homozygous familial hypercholesterolaemia may be treated with 40 mg once daily in the evening, or 80 mg daily in three divided doses of 20 mg, 20 mg, and an evening dose of 40 mg. A maximum of 10 mg daily is recommended in those taking ciclosporin, fibric acid derivatives, or nicotinic acid, and the risk of myopathy must be considered.
  • Precaution!
  • Before instituting therapy with Simvastatin, an attempt should be made to control hypercholesterolaemia with appropriate diet, exercise, and weight reduction in obese patients and to treat other underlying medical problems, monitor liver function test during treatment. It should be discontinued if marked or persistent increases in serum-aminotransferase or creatinine-phosphokinase concentrations occur. It should be used with caution in patients with severe renal impairment.

  • TERRAMEDIC INC.
  • E & E Industrial Comaplex, Narra Road
  • Brgy, San Antonio San Pedro Laguna
  • Tel Nos:  556-7946, 556-7689 , 556-7886
  • Telefax:  556-8302
  • PARTNER COMPANIES
  • Terramedic Inc. | Drugmakers Partner