• (Amoxicillin Trihydrate)

  • Terramedic Products

  • How does it work?
  • AMOXICILLIN chemically known as p-hydroxyampicilin, is a semi-synthetic product derived from acetylated 6 - aminopenicillanic acid. It differs from other penicillin in that AMOXICILLIN has a broad-spectrum antimicrobial activity effective against most Gram-negative and Gram-positive microorganisms. Furthermore, it is superior to both Penicillin G and Ampicillin in that AMOXICILLIN is more acid stable and is better suited for oral use. AMOXICILLIN is more rapidly and nearly 100% absorbed from the gastrointestinal tract such as that peak concentrations in plasma are 2 to 2½ times quarter for AMOXICILLIN than for ampicillin after oral administration of the same dose. Peak plasma concentration is reached at 2 hours and average about 4 ug / mL when 250 mg is administered. Food does not interfere with absorption thus, the incidence of diarrhea is less. Effective concentration of AMOXICILLIN is detectable in the plasma for twice as long as with ampicillin because of its complete absorption. AMOXICILLIN is 17% protein bound with a half-life of about 1 hour. Approximately 50% of a dose of AMOXICILLIN is excreted in an active form in the urine.
  • How is it taken?
  • Children:
    20 - 40 mg / Kg body weight per day in 3 equal doses to be given 8 hourly. Or as prescribed by the physician.
    2 - 6 years: - 1 teaspoonful (2.5 mL - 5 mL)
    7 -12 years: 1 -2 teaspoonful (7.5 mL -10 mL)
    Every 8 hours or as prescribed by the physician.
    Oral Drops:
    20 - 40 mg / Kg body weight / day divided into three equal doses
    Below 1 month : 0.25 mL
    1 - 6 months : 0.5 mL
    7 - 12 months : 0.75 mL
    1 - 3 years old : 1 mL
    Every 8 hours or as prescribed by the physician.
  • Precaution!
  • As with any penicillin preparations, a careful inquiry about past sensitivity or allergic reactions to penicillin or other antigens should be made for reactions to oral penicillin are more likely to occur in hypersensitive individuals. Should an allergy occur, the drug should be discontinued and the patient should be treated with a usual agents (antihistamines, pressor amines or corticosteroids). A transient and moderate elevation of serum glutamic oxaloacetic transaminase has been noted in few infants, but the significance of this finding cannot be determined at present. It is advisable, however, to perform liver or kidney function tests on the hematopoietic system during therapy, particularly in infants. Safety for use in pregnancy has not been determined. However the penicillin is apparently non-teratogenic in humans.

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  • Brgy, San Antonio San Pedro Laguna
  • Tel Nos:  556-7946, 556-7689 , 556-7886
  • Telefax:  556-8302
  • Terramedic Inc. | Drugmakers Partner